MK-677 is a growth hormone secretagogue. A growth hormone secretagogue amplifies the body’s natural release of growth hormone such as when in deep REM sleep, first thing in the morning and after intense exercise.
The hormones that affect growth in mammals are; growth hormone (GH), insulin, Insulin-like Growth Factor-1 (IGF-1), thyroid hormones, glucocorticoids, prolactin, and gonadal steroids (androgens and estrogens). Their role in growth and development has traditionally been investigated by examining the effect of hormone deprivation after organ ablation; the effects of excess amounts of hormones can be observed by administering the hormones to animals in vivo.
Growth hormone (GH) is generally known and believed to be the most important hormone affecting growth and development. Clinical observations show that GH deficiency in children results in dwarfism and that excess GH results in acromegaly and gigantism. [R]
The levels of Growth hormone (GH) will determine the quality of the proteins which make up the body. GH is also mainly responsible for other factors such as biological age, hormone balance, muscle quality, body fat levels, skin elasticity, connective tissue quality and causes large improvements in sleep quality and training recovery.
Infact, the increase of Growth Hormone (hGH) levels in humans results in rapid wound healing may reduce the hypermetabolic period, the risk of infection, and accelerate the healing of donor sites used for grafting onto burned areas. [R]
A growth hormone secretagogue amplifies the body’s natural release of growth hormone such as when in deep REM sleep, first thing in the morning and after intense exercise.
MK-677 has demonstrated in studies to increase the release of, and produce sustained increases in plasma levels of several hormones including GH and insulin-like-growth-factor 1 (IGF-1) for up to 24 hours. In another study, a short 8 week treatment with MK-677 in healthy obese males caused a sustained increase in serum levels of GH, IGF-I, and IGF-binding protein-3. The effects on cortisol secretion were transient (cortisol was temporarily lowered while on the MK-677 but then returned to baseline when ceased). The transformations in body composition (physique) and energy expenditure were of an anabolic nature, with a sustained increase in fat-free muscle mass and an increase in basal metabolic rate. [R]
Dosage of MK-677
Research suggests this compound (MK-677) is effective dosed at 12.5mg – 25mg per day. Each bottle has 750mg of MK-677. 1ml of Elite Sarms GH Pep is equal to 25mg of MK-677. Each bottle contains 30 + dosages. Research cycle length: 8 – 12 Weeks. Shake well before use.
